CHRONIC LEAD POISONING

Nephropathy in chronic lead poisoning.

This paper presents a study of renal function in I02 patients with lead poisoning admitted to the Occupational Diseases Clinic in Bucharest during the past IO years; nearly half the patients had no history of lead colic. Every possible cause of renal damage, other than lead, was excluded by a careful differential diagnosis. Renal function was investigated by repeated determinations of blood ure...

EFFECT OF CHRONIC LEAD POISONING ON ERYTHROCYTE PROTOPORPHYRIN IN RATS

Research has shown that exposure to lead may have adverse effects at different blood lead concentrations. Lead inhibits at least two enzymes that are essential for the formation of heme, and because of the interaction of lead with these enzymes, no iron is inserted into protoporphyrin. Therefore the concentration of protoporphyrin increases in erythrocytes. The concentration of lead was mea...

Chronic neurological disease as a possible form of lead poisoning.

It has long been known that the clinical manifestations of lesions in the nervous system produced by lead are diverse and may simulate the symptoms of various chronic neurological diseases. This suggested to early workers that lead might be an aetiological agent in such diseases. Later, the failure to demonstrate the presence of other features of classical lead poisoning such as colic, anaemia,...

Lead Poisoning in Its Acute and Chronic Forms

Chronic lead poisoning in an adult battery worker.

BACKGROUND Lead poisoning is a common environmental health hazard in developing countries. Incidences of lead poisoning are seen in all age groups, especially in adults working in lead-based industries, where many still remain unaware of the adverse effects of exposure to unusually high levels of lead. METHODS We report the case of an adult battery worker, who initially received symptomatic t...